Neoantigens Market By Treatment (Combination Therapy and Mono Therapy);By Therapeutic Specialty (Lung Cancer, Urinary System Cancer, Melanoma, Liver Cancer, Head and Neck Cancer, and Blood, Bone Marrow Cancer, and Other); By Product (Personalized Neo-Antigen Vaccine, Off-The Shell Neo-Antigen Vaccine); By End User (Hospitals, research and academic institutions, contract research organizations (CROs), and Others); By Region (North America, Europe, Asia Pacific, Latin America, Middle East & Africa) - Global Market Analysis, Trends, Opportunity and Forecast, 2022-2032
Neoantigens Market Insights
Neoantigens are proteins formed on cancer cells due to mutations in tumor DNA, playing a crucial role in the development of cancer vaccines and immunotherapies. As these proteins are recognized as foreign by the host's immune system, they hold significant potential in cancer immunoediting - a technique utilized to understand the dual roles of the immune system in tumor growth. Various clinical trials have demonstrated promising results with neoantigen-based vaccines and targeted therapies, as they can control tumor growth, facilitate cellular transformation, and impact the immunogenicity of tumors. Neoantigens can be classified into two categories: personalized and shared. Personalized neoantigens are specific to an individual's genome, while shared neoantigens are not. Accurate prediction of the number of neoantigens is essential and relies on well-validated algorithms to select reliable neoepitopes. The process of developing a neoantigen cancer vaccine involves obtaining tumor tissue from the patient, identifying mutant genes in the tumor, and conducting RNA/DNA sequencing tests to select appropriate mutated antigens. These antigens are then incorporated into tailor-made vaccines.
Neoantigens Market Size and Share
The neoantigens market refers to the various products and services related to the identification and characterization of neoantigens, which are antigens that are not present in normal cells and are specific to cancer cells. The market for neoantigens is expected to grow in the coming years as these technologies and therapies become more widely adopted. The worldwide neoantigens market was valued at approximately USD 1.15 billion in 2022 and is projected to succeed in USD 10.9billion by 2032, with a compound annual rate of growth (CAGR) of 25.3 % during the forecast period (2023-2032).
Neoantigens Market: Report Scope |
|
|
Base Year |
2022 |
|
Base Year Market Size |
$1.15 billion |
|
Forecast Year |
2023-2032 |
|
Forecast Year Market Size |
$10.9 billion |
|
CAGR Value |
25.3% |
|
Segmentation |
|
|
Challenges |
|
|
Growth Drivers |
|
Neoantigens Market Driving Factors
Some of the key factors driving the growth of the neoantigens market include:
- Advancements in next-generation sequencing technology: The increased use of next-generation sequencing (NGS) technology has resulted in the identification of an increasing number of neoantigens, which is boosting the market for neoantigen-based cancer treatments.
- Increasing incidence of cancer: The rising cancer incidence worldwide is likely to fuel demand for neoantigen-based treatments, which are designed to selectively target cancer cells.
- Adoption of personalized medicine: The increasing use of personalized medicine in cancer, which involves the use of genetic information to adapt therapy to the individual patient, is, therefore, likely to fuel market expansion.
- A growing interest in immuno-oncology: As neoantigens are significant targets in this sector, the growing interest in immuno-oncology, which includes harnessing the immune system to combat cancer, is projected to promote market growth.
- Development of cancer vaccines targeting neoantigens: As these vaccinations are meant to selectively target cancer cells, the development of cancer vaccines targeting neoantigens is therefore likely to boost market growth.
Neoantigens Market Key Trend & Development
There are several key trends and development in the field of the Neoantigens Market
- Increasing Investment in Neoantigen-Based Therapeutics: Investments in the neoantigen market have increased, and many biotechnology and pharmaceutical companies are developing neoantigen-based therapies by 2027.
- Advances in genomic sequencing: The development of high-throughput genomic sequencing technologies has enabled the detection of mutations in tumors, leading to the identification of novel antigens This has opened the door to the development of synthetic cancer vaccines for each and targeted treatments.
- A growing interest in combination therapy: Researchers are exploring the potential of combining neoantigen-based therapies with other cancer therapies, such as checkpoint inhibitors, to boost immune responses and promote healing developed.
- Cooperation between academic institutions and industry: Cooperation between academic institutions and industry players led to the development of new neoantigen-based therapies Collaboration facilitated the validation of new antigen prediction systems and the discovery of new clinically relevant antigens.
Neoantigens Market Segmentation
The neoantigens market can be segmented based on several criteria, including:
- Treatment: Combination Therapy and Mono Therapy
- Therapeutic Specialty: Lung Cancer, Urinary System Cancer, Melanoma, Liver Cancer, Head and Neck Cancer, and Blood, Bone Marrow Cancer, and Other
- Product: Personalized Neo-Antigen Vaccine, Off-The Shell Neo-Antigen Vaccine
- End User: Hospitals, research and academic institutions, contract research organizations (CROs), and Others
- Geography: This segment includes regional markets such as North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.
Neoantigens Market Regional Synopsis:
With a big share of the worldwide market, North America is the largest marketplace for Neoantigens. By 2032, the market is predicted to be worth $5.3 billion, growing at a CAGR of 27.9% (2023-2032), with the USA serving as the region's largest market against an earlier estimation of worth $460 million in 2022.
Europe is another important marketplace for Neoantigens, with Germany, France, and Italy having a high prevalence of health conditions. The presence of major pharmaceutical companies within the region has an impression on the market. By 2032, the market is predicted to be worth $2.67 billion, growing at a CAGR of 25.0% (2023-2032) against an earlier estimation of worth $287.5 million in 2022.
The Neoantigens market is predicted to expand significantly within the Asia-Pacific region thanks to improved healthcare infrastructure. The region's primary markets are Japan, China, and India. With a CAGR of 29.9% (2023-2032), the market is predicted to succeed in $ 3.14 billion by 2032 against an earlier estimation of worth $230 million in 2022.
Although the marketplace for Neoantigens in Latin America is comparatively small, it's anticipated to expand significantly within the coming years' thanks to improved regional healthcare infrastructure. With a CAGR of 23.4% (2023-2032), the market is predicted to succeed in $941.5 million by 2032 against an earlier estimation of worth $115 million in 2022.
The Middle East and African marketplace for Neoantigens is relatively small, but it's expected to grow within the coming years because the region's healthcare infrastructure gets better. By 2032, the market is predicted to be worth $359 million, growing at a CAGR of 20.1% (2023-2032) against an earlier estimation of worth $57.5 million in 2022.
Neoantigens Market Challenges
Some of the key challenges facing the neoantigens market include:
- High cost: Identifying and characterizing neoantigens is capable of be an expensive procedure, potentially limiting market expansion by means of making these medicines less accessible to patients.
- Lack of standardization: There is currently a deficiency of standardization in the discovery and characterization of neoantigens, which makes comparing data across various research and clinical trials challenging.
- Limited understanding of neoantigens: The processes by which neoantigens cause cancer are not well known, which makes developing effective medicines targeting these antigens problematic.
- The complexity of the immune system: The immune system is a complicated system, and understanding how to successfully target neoantigens within this system is difficult.
- Limited clinical data: Because there is currently limited clinical evidence on the effectiveness of neoantigen-based medicines, determining the appropriate technique for treating cancer with these therapies is capable of be challenging.
Neoantigens Market Key Players
Some of the key players in the neoantigens market include:
- Moderna Therapeutics: Moderna Therapeutics is a biotechnology business that develops personalized cancer treatments that tarreceive neoantigens using messenger RNA (mRNA) technology. The company has various cancer treatments with neoantigen structures.
- Gritstone Oncology: A biotechnology firm producing personalized cancer vaccinations that obtain neoantigens. GRANITE, Gritstone's flagship product candidate, is now undergoing Phase II clinical studies for solid tumors.
- BioNTech: A biotechnology firm that is working on cancer vaccinations that tarreceive neoantigens. BioNTech develops personalized cancer medicines that are obtained from neoantigens using mRNA technology.
- Inivata: A liquid biopsy startup working on non-invasive testing for finding neoantigens in cancer patients. The technology developed by means of Iniwata has the potential to improve cancer detection and medical diagnostics.
- Adaptive Biotechnologies: A biotechnology firm that specializes in employing next-generation sequencing (NGS) technology to find neoantigens in cancer patients. ImmunoSEQ, the company's technology, employs NGS to sequence T-cell receptors and detect neoantigens.
- Freenome: A liquid biopsy company working on non-invasive diagnostics for finding neoantigens in cancer patients. The company's software, Freenome AI, analyses circulating tumor DNA and identifies novel antigens using machine learning algorithms.
- Agenus Inc. is a biotechnology business that is working on cancer vaccines that tarreceive neoantigens. AutoSynVax, a personalized cancer vaccine now in Phase I clinical studies including several solid tumors, is the company's lead product candidate.
- NeoVax: A biotechnology business that is working on cancer vaccines that tarreceive neoantigens. NeovaxID, the company's technology, identifies neo-antigens and develops personalized cancer vaccinations using DNA sequencing and machine learning algorithms.
- BioAtla: A biotechnology firm working on cancer vaccinations that obtain neoantigens. CAB (Conditionally Active Biologics) is the company's technology that leverages patented protein engineering to generate personalized cancer medicines that tarreceive nine unique antigens.
- Immunocore is a biotechnology business that is working on cancer vaccinations that obtain neoantigens. ImmTAX, the company's platform, identifies new antigens and develops personalized cancer therapeutics using T-cell receptor (TCR) technology.
Make This Report Your Own
Take Advantage of Intelligence Tailored to your Business Objective
Get a Customized Version
- Publication date: 12th October 2023
- Base year: 2022
- Forecast year: 2023-2033
- Format: PDF, PPT,Word,Excel
- Quick Contact -
- ISO Certified Logo -
Frequently Asked Questions(FAQ)
Neoantigens Market
-: Our Clients :-
