Duchenne Muscular Dystrophy Treatment Market : Global Size, Share, Trends, Growth and Forecast Year ( 2022 – 2032 )
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- Status : Published
- Published on: Feb 2023
- Report ID: KDMI-7123
- Available Format: PDF/Excel/DOC
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Duchenne Muscular Dystrophy (DMD) Treatment Market Insights:
Duchenne Muscular Dystrophy (DMD), a rare genetic disorder, results in progressive muscle weakness and degeneration. It currently doesn't have a cure, but there are treatments that will help manage symptoms and improve quality of life. The pharmaceuticals, treatments, and devices within the DMD treatment market are all aimed at controlling the disease's symptoms, halting its progression, and enhancing patients' quality of life. Two of the foremost common treatments for DMD are; Corticosteroids, which increases muscle strength and delay the onset of respiratory and cardiac complications, and gene therapy, which involves inserting functional copies of the dystrophin gene into the patient's cells.
Some of the latest trends in the treatment of Duchenne Muscular Dystrophy (DMD) include:
- Gene therapy: This experimental treatment aims to bring back a functioning copy of the defective gene that causes DMD. Several companies are developing DMD gene therapy strategies, and clinical trials are ongoing.
- Exon skipping: This is a type of gene therapy that targets the disease-causing dystrophin gene's specific sections (exons). It might be possible to make a dystrophin protein that is shorter but still useful by "skipping" these exons.
- Stem cell therapy: Another experimental treatment that uses stem cells to fix damaged muscle tissue is this one. The use of stem cells to treat DMD is the subject of several clinical trials.
- Antisense oligonucleotides: These are tiny fragments of DNA or RNA that can be used to "silence" the DMD-causing defective gene. For the treatment of DMD, antisense oligonucleotides are currently the subject of clinical trials.
- Clinical trials: Participating in one of the many DMD clinical trials that are currently being conducted may grant access to novel and experimental treatments. It is essential to discuss the advantages and disadvantages of participating in a clinical trial with a medical professional.
Duchenne Muscular Dystrophy (DMD) Treatment Market
As more people become conscious of the disease with new and artistic treatments developed, it's anticipated that the worldwide marketplace for DMD treatments will expand significantly within the coming years. The market for DMD treatment worldwide was worth $1.8 billion in 2020 and is anticipated to expand at a CAGR of 37.5% from 2021 to 2028. By 2028, the market is predicted to be worth $22.5 billion due to rising investments in R&D, increased public awareness of DMD, and therefore the disease's increasing prevalence. Additionally, it's anticipated that the expanding use of exon-skipping drugs and gene therapy will contribute to plugging expansion.
Some of the treatments used in the management of DMD include:
- Corticosteroids: These drugs help to scale back muscle inflammation and improve muscle strength.
- Physical therapy: This will help to enhance muscle strength, flexibility, and range of motion.
- Assistive devices: Devices like wheelchairs, leg braces, and standing frames can help individuals with DMD maintain mobility and independence.
- Gene therapy: This is often an experimental treatment that aims to exchange the defective gene liable for DMD with a functional copy.
- Heart and lung medications: People with DMD are in danger of developing heart and lung problems, and should need medications to manage these conditions.
- Nutrition: A healthy diet and adequate calorie intake are important for people with DMD to take care of strength and muscle mass.
Duchenne Muscular Dystrophy (DMD) Treatment Market Driving Factors:
Several factors are driving the growth of the Duchenne muscular dystrophy (DMD) treatment market:
- Advances in medical technology: In recent years, significant advancements in medical technology have resulted in the creation of novel DMD treatments. Stem cell therapy, gene therapy, and drugs that skip exons are some of the promising treatments being developed for DMD.
- Favourable regulatory environment: New therapies for rare diseases like DMD are getting more and more support from regulatory bodies all over the world. The market is expanding as a result of an increase in the number of clinical trials and approvals for DMD treatments.
- Government support: Treatments for rare diseases, such as DMD, receive support and funding from numerous governments. The market for DMD treatments is likely to expand as a result.
- Growing research and development activities: Within the treatment of DMD, there's tons of research and development happening with the goal of arising new treatments that is employable. This has resulted in the discovery of a variety of novel treatment options and is anticipated to propel market expansion within the upcoming years.
- Increasing awareness about DMD: In recent years, more people are diagnosed with DMD and have sought treatment as a result of a rise in awareness which is often likely to support the expansion of the DMD treatment market.
- Increasing healthcare expenditure: As people live longer and therefore the cost of healthcare continues to rise, there's likely to be a rise in spending on treatments for DMD and other rare diseases.
- Increasing prevalence of DMD: DMD may be a genetic disease that happens in only a few people, but it's more common than other rare diseases. The Muscular Dystrophy Association states that DMD affects roughly one in every 5,000 male births. The market is expanding due to the rising demand for effective treatments and therefore the rising prevalence of DMD.
Duchenne Muscular Dystrophy (DMD) Treatment Market Segmentation:
The Duchenne muscular dystrophy (DMD) treatment market can be segmented based on treatment type, stage of development, end user, and region:
By Treatment Type
- Gene therapy
- Physical therapy
By End-user Type
By Stage of Development Type
- Phase I/II Clinical Trials
- Phase III Clinical Trials
- Approved therapies
By Region Type
- North America
- Latin America
- Middle and East Africa
Duchenne Muscular Dystrophy (DMD) Market by Treatment Type review:
Corticosteroids are a class of medications that are frequently used to treat DMD. They reduce inflammation and slow the disease's progression. With an estimated $1.1 billion market share in 2020, they are anticipated to expand at a CAGR of 34.8% from 2021 to 2028. In gene therapy, a functional copy of the dystrophin gene is inserted into the patient's cells to aid in the production of the missing protein. With a CAGR of 44.4% from 2021 to 2028, the gene therapy market is expected to expand at the fastest rate against a market value of $117.3 million in 2020. Patients with DMD can benefit from physical therapy and exercise programs to maintain muscle strength and mobility. From an estimated value of $260.3 million in 2020, the market is expected to expand at a CAGR of 36.4% from 2021 to 2028. Orthopedic interventions like braces and corrective surgery, as well as respiratory support like ventilators and cough assist devices, fall under the category of "others" whose estimated value was $306.2 million in 2020, and is anticipated to expand at a CAGR of 38.3% from 2021 to 2028.
Duchenne Muscular Dystrophy (DMD) Market by End-user Type review:
From 2021 to 2028, the hospital segment is anticipated to expand at a CAGR of 36.0%, representing the largest market share in 2020. As the primary provider of healthcare for DMD patients, hospitals were estimated to have a market value of $1.3 billion in 2020. The segment is anticipated to grow at a CAGR of 38.6% from 2021 to 2028 from an estimated value of $540.2 million in 2020. Clinics are another important healthcare provider for DMD patients, particularly for physical therapy and other supportive care. Home healthcare, rehabilitation centers, and long-term care facilities are all included in the "others" category. From 2021 to 2028, this market is anticipated to expand at a CAGR of 37.4% at a market value of $205.3 million in 2020.
Duchenne Muscular Dystrophy (DMD) Market by Stage of Development Type review:
Therapeutics within the preclinical stage remain within the testing stage and haven't yet received human use approval. From an estimated market price of $1.1 billion in 2020, this sector is anticipated to expand at a CAGR of 35.9% from 2021 to 2028. The therapies in the phase I/II clinical trials segment are still within the early stages of clinical testing, typically with limited patient populations. From 2021 to 2028, this market is predicted to expand at a CAGR of 36.5%, against worth of $1.4 billion in 2020. The phase III clinical trial Clinical Trials segment is nearing approval for commercial use and has advanced to larger-scale clinical trials. From 2021 to 2028, this market is anticipated to expand at a CAGR of 37.4%. In 2020, it had been predicted that therapies from phase III clinical trial clinical trials would have a market price of $1.1 billion. Therapies that have received regulatory approval for commercial use are included within the approved Therapies segment. From 2021 to 2028, this market is anticipated to expand at a CAGR of 34.6%. In 2020, it had been predicted that approved therapies would have a market price of $550,6 million.
Duchenne Muscular Dystrophy (DMD) Market by Region Type review:
With over 40% of the global market, North America held the largest market share in 2020. With an expected CAGR of 36.5% from 2021 to 2028, the region will continue to dominate the market against a market value of $1.7 billion in 2020. With over 25% of the global market, Europe is the second largest market for DMD treatment which is anticipated to expand at a CAGR of 35.9% from 2021 to 2028 having a market value estimated to be $1.1 billion in 2020. With a CAGR of 39.8% from 2021 to 2028, the Asia-Pacific region is anticipated to experience the fastest growth during the forecast period. In 2020, it was predicted that the Asia-Pacific region would have a market value of $610.4 million. From 2021 to 2028, the Latin American region is anticipated to expand at a CAGR of 37.7%. In 2020, it was predicted that Latin America would have a market value of $138.3 million. From 2021 to 2028, the Middle East and Africa region is anticipated to expand at a CAGR of 34.6%. In 2020, it was predicted that the Middle East and Africa would have a market value of $109.8 million.
Duchenne Muscular Dystrophy (DMD) Treatment Market Challenges:
There are several challenges facing the Duchenne muscular dystrophy (DMD) treatment market.
- Access to healthcare: Access to healthcare for people with DMD may be difficult, especially in areas with limited healthcare infrastructure or resources. DMD treatments may be limited in scope and impact as a result.
- Competitive landscape: There are a lot of companies competing for market share in the DMD treatment market. New entrants and established players may find it challenging to maintain their market position as a result.
- Complex disease biology: DMD is a complicated condition characterized by a wide range of symptoms and genetic mutations. Researchers and clinicians may find it challenging to manage the disease and develop effective treatments as a result of this complexity.
- High cost of treatment: DMD treatments are very expensive, making it hard for patients to urge them and buy them. this might limit the utilization of the latest treatments for a few patients who cannot afford them and hinder market expansion.
- Lack of cure and approved therapies: DMD doesn't currently have a cure, and lots of the treatments that are available can only manage the disease's symptoms. With only a couple of approved treatments, none of them being highly effective, patients are left with few treatment options which can limit the market's expansion.
- Limited patient pool: DMD is a rare disease with a relatively small patient pool, which can make it difficult for companies to conduct clinical trials, obtain regulatory approval, and generate sufficient revenue.
- Regulatory challenges: The regulatory environment for DMD treatments can be challenging because before approving new therapies, regulatory agencies frequently require extensive clinical data as well as evidence of long-term safety and efficacy. Companies working on new DMD treatments may face difficulties as a result.
- Reimbursement issues: Patients' inability to obtain insurance coverage for DMD treatments may hinder their access to care in some instances.
Duchenne Muscular Dystrophy (DMD) Treatment Key Players
There are several key players in the Duchenne muscular dystrophy (DMD) market, including:
- Sarepta Therapeutics
- Santhera Pharmaceuticals
- Taiho Pharmaceuticals
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